API TOPIROXOSTAT CAS 577778-58-6
Topiroxostat is a API for metabolic arthritis and hyperuricemia, it’s an inhibitor of xanthine oxidoreductase, an enzyme that converts xanthine to urate. Formulations containing topiroxostat are effective in vivo, lowering urate levels in the serum of patients with hyperuricemia. In rats, but not primates, topiroxostat treatment results in the formation of xanthine crystals, resulting in nephritis.